Incidence:  Epilepsy disorders are estimated to affect approximately 3 million Americans of all ages and ethnic groups, with a lifetime risk to age 80 of 3%. The incidence of epilepsy is highest in early childhood and is growing fastest in the elderly population.  (

Medical Cannabis Indication: Epilespy    

          Improves:  Neurological disturbances, Cognitive function, Physical function,

                            Appetite, Sleep

Recommended cannabinoid ratios:  

                     low THC: high CBD (e.g. 1:20)

                     equal ratio THC: CBD (e.g. 1:1) 

                     high THC : low CBD (e.g. 20:1)

Higher CBD ratios than a 1:20 is ineffective for about 70% of patients with epilepsy.


Go slow and start dosing low and titrate until desired results are achieved.

 (Combination of  the above products may be required).  THC doses greater than 10mg/dose not recommended


Neuroprotective properties may improve condition.

Cannabinoid replacement therapy may reduce symptoms and prolong survival. 

(Please note that cannabinoid therapy is patient specific and may require dose/concentration adjustment. Please consult with your provider for appropriate therapy options.)


References and Journal Articles: 

Dr. Devinsy:  Cannabidiol: Pharmacology and potential therapeutic role in epilepsy and other neuropsychiatric disorders

The Endogenous Cannabinoid System Regulates Seizure Frequency and Duration in a Model of Temporal Lobe Epilepsy

A Case for Medical Marijuana and Epilepsy:  Case Report: Charlotte Figi

Cannabinoids: is there a potential treatment role in epilepsy?  Robert E Blair , Laxmikant S Deshpande & Robert J DeLorenzo

Marijuana derivatives in epilepsy treatment in childhood -Current knowledge Anna Makulec, Wladyslaw Lason, Sergiusz Jozwiak