Incidence: Epilepsy disorders are estimated to affect approximately 3 million Americans of all ages and ethnic groups, with a lifetime risk to age 80 of 3%. The incidence of epilepsy is highest in early childhood and is growing fastest in the elderly population. (https://report.nih.gov/nihfactsheets/ViewFactSheet.aspx?csid=88&key=E)
Medical Cannabis Indication: Epilespy
Improves: Neurological disturbances, Cognitive function, Physical function,
Recommended cannabinoid ratios:
low THC: high CBD (e.g. 1:20)
equal ratio THC: CBD (e.g. 1:1)
high THC : low CBD (e.g. 20:1)
Higher CBD ratios than a 1:20 is ineffective for about 70% of patients with epilepsy.
Go slow and start dosing low and titrate until desired results are achieved.
(Combination of the above products may be required). THC doses greater than 10mg/dose not recommended
Neuroprotective properties may improve condition.
Cannabinoid replacement therapy may reduce symptoms and prolong survival.
(Please note that cannabinoid therapy is patient specific and may require dose/concentration adjustment. Please consult with your provider for appropriate therapy options.)
References and Journal Articles:
Dr. Devinsy: Cannabidiol: Pharmacology and potential therapeutic role in epilepsy and other neuropsychiatric disorders
A Case for Medical Marijuana and Epilepsy: Case Report: Charlotte Figi
Cannabinoids: is there a potential treatment role in epilepsy? Robert E Blair , Laxmikant S Deshpande & Robert J DeLorenzo
Marijuana derivatives in epilepsy treatment in childhood -Current knowledge Anna Makulec, Wladyslaw Lason, Sergiusz Jozwiak