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Incidence:  Epilepsy disorders are estimated to affect approximately 3 million Americans of all ages and ethnic groups, with a lifetime risk to age 80 of 3%. The incidence of epilepsy is highest in early childhood and is growing fastest in the elderly population.  (https://report.nih.gov/nihfactsheets/ViewFactSheet.aspx?csid=88&key=E)

Medical Cannabis Indication: Epilespy    

          Improves:  Neurological disturbances, Cognitive function, Physical function,

                            Appetite, Sleep

Recommended cannabinoid ratios:  

                     low THC: high CBD (e.g. 1:20)

                     equal ratio THC: CBD (e.g. 1:1) 

                     high THC : low CBD (e.g. 20:1)

Higher CBD ratios than a 1:20 is ineffective for about 70% of patients with epilepsy.

Dosing:  

Go slow and start dosing low and titrate until desired results are achieved.

 (Combination of  the above products may be required).  THC doses greater than 10mg/dose not recommended

Other:  

Neuroprotective properties may improve condition.

Cannabinoid replacement therapy may reduce symptoms and prolong survival. 

(Please note that cannabinoid therapy is patient specific and may require dose/concentration adjustment. Please consult with your provider for appropriate therapy options.)

 

References: 

Dr. Devinsy:  Cannabidiol: Pharmacology and potential therapeutic role in epilepsy and other neuropsychiatric disorders

The Endogenous Cannabinoid System Regulates Seizure Frequency and Duration in a Model of Temporal Lobe Epilepsy

A Case for Medical Marijuana and Epilepsy:  Case Report: Charlotte Figi

Journal Articles: